There are two reasons that kidney disease can cause renal Hypertension.
One is renin. Renin secreted by kidneys is just enough in a normal human
body, so it will not cause high blood pressure. When there are pathological
changes in kidneys or kidney vessels, the secretion of renin will increase
dramatically, which can lead to arteriolar spasm. Therefore, arteriole
resistance increased, and then followed by Hypertension. The incidence, duration
and elevated blood pressure level of Hypertension are related to kidney damage
degree
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and pathological changes. For example: The duration of Hypertension is
shorter and blood pressure will return normal in 2 to 3 weeks when suffering
acute Nephritis; The duration of blood pressure is longer and it is difficult to
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The other is the decrease of anti-vasopressor substances secretion. When
there are pathological changes in renal parenchyma, the secretion of
prostaglandin synthesis decreases while the secretion of renin increases
dramatically. The disorder of the two secretion lead to high blood pressure.
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