2015年12月22日星期二

How does Renal Osteodystrophy Occur?

Renal refers to the kidneys. Renal osteodystrophy is a bone disease that occurs
when kidneys fail to maintain the proper levels of calcium and phosphorus in the blood. It's common to patients with kidney disease especially patients has taken dialysis.
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Renal osteodystrophy is most serious in children because their bones are still growing. The disease can lead to deformities and short stature. Symptoms can be seen in growing children with renal disease even before they start dialysis. The bone changes from renal osteodystrophy can begin many years before symptoms appear in adults with kidney disease. The symptoms of renal osteodystrophy usually can not be seen in adults until they have been on dialysis for several years. If left untreated, the bones gradually become thin and weak, and a person with renal osteodystrophy may begin to feel bone and joint pain. There's also an increased risk of bone fractures.What Medicines Can Help Kidney Failure without Dialysis
The pathogeny of renal osteodystrophy is related to metabolic disorders Of Calcium, Phosphorus and Vitamin D.How Can Kidney Failure Patients with Creatinine 14.6 Be Cured
If calcium levels in the blood become too low, the parathyroid glands can release a hormone called parathyroid hormone (PTH). This hormone draws calcium from the bones to raise blood calcium levels. Too much PTH in the blood will remove too much calcium from the bones; over time, the constant removal of calcium weakens the bones.Is There Any Way to Treat Kidney Failure to Go Back to Normal
Phosphorus can regulate calcium levels in the bones. Healthy kidneys can remove excess phosphorus from the blood. When the kidneys stop working normally, phosphorus levels in the blood can become too high, leading to lower levels of calcium in the blood and resulting in the loss of calcium from the bones

Healthy kidneys produce calcitriol, a form of vitamin D, which can help the body absorb calcium in diet into the blood and the bones. Calcitriol and PTH work together to keep calcium balance and bones healthy. If calcitriol level drop too low and PTH level increase, calcium will be removed from the bones. In a patient with kidney failure, the kidneys stop making calcitriol. The body then can't absorb calcium from food and starts removing it from the bones.

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